Blar i forfatter "Khider, Miriam"
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The alternative sigma factor RpoQ regulates colony morphology, biofilm formation and motility in the fish pathogen Aliivibrio salmonicida
Khider, Miriam; Willassen, Nils Peder; Hansen, Hilde (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-12)<i>Background</i>: Quorum sensing (QS) is a cell-to cell communication system that bacteria use to synchronize activities as a group. LitR, the master regulator of QS in <i>Aliivibrio salmonicida</i>, was recently shown to regulate activities such as motility, rugosity and biofilm formation in a temperature dependent manner. LitR was also found to be a positive regulator of <i>rpoQ</i>. RpoQ ... -
Differential expression profiling of ΔlitR and ΔrpoQ mutants reveals insight into QS regulation of motility, adhesion and biofilm formation in Aliivibrio salmonicida
Khider, Miriam; Hjerde, Erik; Hansen, Hilde; Willassen, Nils Peder (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-15)<i>Background</i>: The coordination of group behaviors in bacteria is achieved by a cell-cell signaling process called quorum sensing (QS). QS is an intercellular communication system, which synchronously controls expression of a vast range of genes in response to changes in cell density and is mediated by autoinducers that act as extracellular signals. <i>Aliivibrio salmonicida</i>, the causative ... -
Exploring Quorum Sensing Dynamics and Biofilm Formation in the Fish Pathogen Aliivibrio salmonicida
Khider, Miriam (Doctoral thesis; Doktorgradsavhandling, 2019-10-22)<p>The marine pathogen <i>Aliivibrio salmonicida</i> is the causative agent of cold-water vibriosis, affecting mainly farmed salmonid fish when water temperatures are below 10°C. Even though cold-water vibriosis is no longer threatening Norwegian aquaculture, the reemergence of the disease is still a possibility. Therefore, it is crucial to gain knowledge and understanding of the pathogenicity ... -
Exploring the transcriptome of luxI- and ΔainS mutants and the impact of N-3-oxo-hexanoyl-L- and N-3-hydroxy- decanoyl-L-homoserine lactones on biofilm formation in Aliivibrio salmonicida
Khider, Miriam; Hansen, Hilde; Hjerde, Erik; Johansen, Jostein A; Willassen, Nils Peder (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-30)<i>Background</i>: Bacterial communication through quorum sensing (QS) systems has been reported to be important in coordinating several traits such as biofilm formation. In <i>Aliivibrio salmonicida</i> two QS systems the LuxI/R and AinS/R, have been shown to be responsible for the production of eight acyl-homoserine lactones (AHLs) in a cell density dependent manner. We have previously ... -
Quorum sensing in Aliivibrio wodanis 06/09/139 and its role in controlling various phenotypic traits
Maharajan, Amudha Deepalakshmi; Hansen, Hilde; Khider, Miriam; Willassen, Nils P (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-24)Background Quorum Sensing (QS) is a cell-to-cell communication system that bacteria utilize to adapt to the external environment by synthesizing and responding to signalling molecules called autoinducers. The psychrotrophic bacterium Aliivibrio wodanis 06/09/139, originally isolated from a winter ulcer of a reared Atlantic salmon, produces the autoinducer N-3-hydroxy-decanoyl-homoserine-lactone ...